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Scandium Chloride Tetrahydrofuran Complex

Chemical Formula: ScCl3·3THF
CAS: 14782-78-6

Scandium Chloride Tetrahydrofuran Complex, also known as ScCl3·3THF, is an important organometallic scandium compound. This compound is a strong Lewis acid and is widely used in organic synthesis, polymerization catalysis, and rare earth materials research. Compared to anhydrous ScCl3, its THF adduct has higher solubility and is easier to handle in laboratory and scale-up reactions.
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Scandium Chloride Tetrahydrofuran Complex Basic Properties

  • Molecular Formula: C12H24Cl3O3Sc

  • Molecular Weight: 367.63

  • Purity: 99%

  • Package Information: 100g; 500g or customized

Scandium Chloride Tetrahydrofuran Complex Key Features

Strong Lewis acidity

ScCl3·3THF exhibits strong Lewis acid activity, effectively activating substrates such as carbonyl compounds and catalyzing various organic transformation reactions, including Friedel-Crafts reactions, thereby enhancing reaction activity and controllability.

High purity

Wolfa offers scandium chloride tetrahydrofuran complexes with a purity of 99% or higher for advanced research and coordination development, ensuring low impurity levels on the reaction system and reliable research results.

Ideal scandium source precursor

Compared to anhydrous scandium trichloride, the scandium atoms in ScCl3·3THF are solvated in tetrahydrofuran, giving it better solubility and ease of handling in organic solvents. This makes it ideal as a starting material for the synthesis of rare earth metal-organic frameworks (MOFs) and other scandium-containing functional materials.

Scandium Chloride Tetrahydrofuran Complex Main Applications

Lewis acid catalysis in organic synthesis

ScCl3·3THF promotes a wide range of C–C and C–O bond-forming reactions, including Diels–Alder cycloadditions, aldol condensations, and selective carbonyl activations in asymmetric or total synthesis.

Polymerization and copolymerization catalysis

Used in the development of rare-earth metal catalysts for living polymerization of olefins, lactides, and cyclic esters.

Rare earth coordination chemistry

Functions as a convenient Scandium(III) precursor for synthesizing coordination complexes and MOFs (metal-organic frameworks).

Academic & medicinal chemistry research

ScCl3·3THF is valuable in exploring enantioselective catalytic systems and developing biologically active organometallic complexes.

Precautions

  1. The scandium chloride tetrahydrofuran complex should be placed in a dry, inert gas (such as nitrogen or argon) protected environment to prevent moisture and airborne humidity from entering.

  2. Avoid storing with strong alkalis, strong reducing agents, oxidizing agents, etc., to prevent reaction failure or the generation of unstable by-products.

  3. Wear appropriate personal protective equipment, such as protective gloves, splash-proof goggles, and lab coats, and conduct the operation in a well-ventilated environment (such as a fume hood).

  4. If the product comes into contact with skin or eyes, immediately rinse with plenty of water for at least 15 minutes and seek medical attention promptly.

  5. We recommend using airtight metal or dry glass ampoule packaging, with inert gas and desiccant protection, to ensure that the purity and activity remain after delivery.

FAQ

1. What does "3THF" in ScCl3·3THF represent?

Here, "3THF" indicates that each molecule of ScCl3 is combined with three molecules of THF (tetrahydrofuran) ligand, i.e., the chemical formula ScCl3·3THF. The inclusion of THF enhances the solubility and handling convenience of scandium chloride in organic solvents.


2. What should I do if I find the product discolored or clumped upon receipt?

If the product discolors, clumps, or becomes damp, it may be due to moisture absorption or mild hydrolysis. It is recommended to immediately transfer it to a desiccant or glove box and open the packaging in a cool, dry, and inert environment. If the product is severely damp or deteriorated, contact the supplier to confirm its purity and suitability for use.


For more information or to purchase Scandium Chloride Tetrahydrofuran Complex(ScCl3·3THF), please feel free to contact us via jomin@wolfabio.com or WhatsApp(+86 18359103607).

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