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1-Methyl-1,4-Cyclohexadiene

Chemical Formula: C7H10
CAS: 4313-57-9

1-Methyl-1,4-Cyclohexadiene (C7H10) is a colorless to nearly colorless transparent liquid with a typical hydrocarbon odor. It belongs to the cyclic olefin family and plays an important role in organic synthesis. Due to its stable cyclic structure and reactivity of double bonds, C7H10 is widely used in medicinal chemistry, materials precursors, and catalysis research, and is indispensable in the production of many fine chemicals.
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1-Methyl-1,4-Cyclohexadiene Basic Properties

  • Molecular Formula: C7H10

  • Appearance: Colorless to almost colorless transparent liquid

  • Molecular Weight: 94.15

  • Melting Point: <-70℃

  • Boiling Point: 114-115 °C(lit.)

  • Density: 0.838 g/mL at 25 °C(lit.)

  • Refractive Index: n20/D 1.471(lit.)

  • Flash Point: 51 °F

  • Solubility: Soluble in most organic solvents such as ethanol and ether, but insoluble in water

  • Package Information: 100g, 500g, 1kg, or customized

1-Methyl-1,4-Cyclohexadiene Key Features

Moderate structural activity

The double bond positions of 1-Methyl-1,4-Cyclohexadiene are fixed and less affected by ring strain, giving it good controllability in hydrogenation, addition, and oxidation reactions.

Excellent stability

Compared to the easy polymerization of open-chain olefins, this cyclic olefin has a more stable structure, making it easier to store and transport, and safer and more reliable in industrial applications.

Stable state

C7H10 is a liquid at room temperature, making it easier to store safely, measure accurately, and transfer in laboratory operations.

Wide range of applications

Its simplicity and predictable reactivity make it a preferred model substrate for studying double bond selectivity, cycloalkane conversion mechanisms, or transition metal catalytic reactions.

1-Methyl-1,4-Cyclohexadiene Main Applications

Organic synthesis intermediates

1-Methyl-1,4-Cyclohexadiene is widely used in multi-step organic synthesis, including aromatization, oxidation, and hydrogenation reactions, and is a common precursor for constructing aromatic compounds.

Medicinal chemistry research

Its structure can serve as a model unit for terpenes, natural products, and polycyclic skeletons, and as a building block for drug lead compounds, facilitating structural optimization exploration.

Materials chemistry precursors

In the development of certain functional materials, these cycloolefins are used as monomers or additives to adjust polymer structure, material properties, or as modifiers.

Fragrances and flavors

C7H10 is a key structural unit in many synthetic fragrances (such as certain molecules with woody or grassy aromas), and can be used to prepare a series of cyclic alcohols, ketones, or olefin intermediates for the formulation of fragrances.

Precautions

  1. 1-Methyl-1,4-cyclohexadiene has a low flash point and high vapor pressure. It should be kept away from open flames and heat sources to avoid the risk of combustion or explosion due to vapor accumulation.

  2. It must be stored in a well-sealed metal or glass container in a cool, dark place with good ventilation to reduce vapor concentration. Ideally, it should be stored under an inert gas (such as nitrogen) to slow down possible oxidation or polymerization.

  3. These types of hydrocarbons react violently with peroxides and strong oxidizers, and should be stored separately to prevent dangerous reactions.

  4. When operating, wear appropriate chemical safety goggles, protective masks, and gloves, and conduct the operation in a fume hood to ensure that vapors are effectively removed and to avoid inhalation.

  5. Prolonged exposure to air may cause slight oxidation; therefore, the time the container is opened and closed should be minimized.

FAQ

1. What is 1-Methyl-1,4-Cyclohexadiene?

It is a cyclic alkene with the chemical formula C7H10, commonly used in organic synthesis, pharmaceutical research, and catalysis. Its double bond structure can serve as a reaction substrate or a molecular building block.


2. What are the typical uses of C7H10 in organic synthesis?

It is commonly used in reactions such as hydrogenation, oxidation, and aromatization, and is also a common precursor for constructing terpene skeletons and polycyclic structures.


3. How to properly store C7H10 to ensure its stability?

It is recommended to store it at low temperature, in an inert atmosphere (such as nitrogen or argon), and away from light. The container must be tightly sealed to minimize the risk of oxidation or polymerization due to contact with air. Check the storage condition regularly.


We are a professional 1-Methyl-1,4-Cyclohexadiene supplier. For more information or to purchase 1-Methyl-1,4-Cyclohexadiene(C7H10), please feel free to contact us via jomin@wolfabio.com.

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