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Molecular Formula: C2H3ClMg
Appearance: Pale yellow transparent liquid
Molecular Weight: 86.8
Boiling Point: 66 °C
Density: 0.980 g/mL at 20 °C
Flash Point: −1 °F
Storage Conditions: 0-6°C
Solubility: Soluble in ether solvents (THF, diethyl ether), but reacts rapidly and decomposes upon contact with water or alcohols
Purity: 1.6 M in THF
Package Information: 100g, 500g, 1kg or customized
Vinylmagnesium chloride offers strong nucleophilicity, enabling it to efficiently participate in key steps such as the introduction, addition, and substitution of C=C double bonds. It is suitable for API and intermediate manufacturers with extremely high reaction efficiency requirements.
It is compatible with a variety of aldehydes, ketones, esters, and halogenated compounds, and can be used to construct complex organic molecules with diverse structures, providing more possibilities for drug design and process optimization.
Its vinyl structure enables it to exhibit excellent chemoselectivity among a variety of electrophilic substrates, significantly reducing the proportion of byproducts and increasing yield, making it suitable for the precise synthesis of complex molecules.
Customers can choose standard concentrations such as 1 M, 1.5 M, or 2 M, depending on the reaction system, or request specific ether solvents to reduce the risk of reagent incompatibility with the system.
Vinylmagnesium chloride is widely used in the construction of key structures of APIs, such as molecules containing vinyl side chains and adducts containing alcohol functional groups. Its excellent reactivity has a core value in pharmaceutical process optimization.
They are commonly used in high-end coating additives, electronic chemicals, and agrochemical intermediates for vinyl introduction or carbon-carbon bond extension, and are key raw materials for many high-performance materials.
Commonly used in research institutions and process laboratories for basic research such as novel reaction development, route screening, and structure expansion, especially for constructing important structures such as allyl alcohols and olefin derivatives.
It should be sealed under an inert gas atmosphere and stored in a cool, dry environment away from heat sources; it is recommended to use a dedicated metal or glass sealed container.
Vinylmagnesium chloride is extremely sensitive to moisture. Upon exposure, it decomposes rapidly and releases heat, which may even cause combustion. Therefore, opening and operation must be carried out under an inert atmosphere (argon or nitrogen).
Contact with inorganic acids, organic acids, and oxidants will cause violent reactions, which may lead to dangerous exothermic reactions and gas releases. Contact with acids and oxidants should be avoided.
If it comes into contact with skin, immediately rinse with plenty of water and clean with soap. Remove any contaminated clothing. If irritation persists, seek medical attention.
1. Can vinylmagnesium chloride be replaced with other solvents instead of THF?
THF is generally the best choice due to its excellent stability and solubility. Diethyl ether can also be used as an alternative, but its stability is slightly lower. For industrial projects, THF is recommended as the primary solvent.
2. Is this reagent suitable for continuous flow reactions?
Some processes have successfully applied it to continuous flow systems, improving safety and reaction efficiency, but it is necessary to ensure that the equipment can meet anhydrous and oxygen-free conditions.
We are a professional Vinylmagnesium Chloride supplier. For more information or to purchase Vinylmagnesium Chloride(C2H3ClMg), please feel free to contact us via jomin@wolfabio.com.
Molecular Formula: C2H3ClMg
Appearance: Pale yellow transparent liquid
Molecular Weight: 86.8
Boiling Point: 66 °C
Density: 0.980 g/mL at 20 °C
Flash Point: −1 °F
Storage Conditions: 0-6°C
Solubility: Soluble in ether solvents (THF, diethyl ether), but reacts rapidly and decomposes upon contact with water or alcohols
Purity: 1.6 M in THF
Package Information: 100g, 500g, 1kg or customized
Vinylmagnesium chloride offers strong nucleophilicity, enabling it to efficiently participate in key steps such as the introduction, addition, and substitution of C=C double bonds. It is suitable for API and intermediate manufacturers with extremely high reaction efficiency requirements.
It is compatible with a variety of aldehydes, ketones, esters, and halogenated compounds, and can be used to construct complex organic molecules with diverse structures, providing more possibilities for drug design and process optimization.
Its vinyl structure enables it to exhibit excellent chemoselectivity among a variety of electrophilic substrates, significantly reducing the proportion of byproducts and increasing yield, making it suitable for the precise synthesis of complex molecules.
Customers can choose standard concentrations such as 1 M, 1.5 M, or 2 M, depending on the reaction system, or request specific ether solvents to reduce the risk of reagent incompatibility with the system.
Vinylmagnesium chloride is widely used in the construction of key structures of APIs, such as molecules containing vinyl side chains and adducts containing alcohol functional groups. Its excellent reactivity has a core value in pharmaceutical process optimization.
They are commonly used in high-end coating additives, electronic chemicals, and agrochemical intermediates for vinyl introduction or carbon-carbon bond extension, and are key raw materials for many high-performance materials.
Commonly used in research institutions and process laboratories for basic research such as novel reaction development, route screening, and structure expansion, especially for constructing important structures such as allyl alcohols and olefin derivatives.
It should be sealed under an inert gas atmosphere and stored in a cool, dry environment away from heat sources; it is recommended to use a dedicated metal or glass sealed container.
Vinylmagnesium chloride is extremely sensitive to moisture. Upon exposure, it decomposes rapidly and releases heat, which may even cause combustion. Therefore, opening and operation must be carried out under an inert atmosphere (argon or nitrogen).
Contact with inorganic acids, organic acids, and oxidants will cause violent reactions, which may lead to dangerous exothermic reactions and gas releases. Contact with acids and oxidants should be avoided.
If it comes into contact with skin, immediately rinse with plenty of water and clean with soap. Remove any contaminated clothing. If irritation persists, seek medical attention.
1. Can vinylmagnesium chloride be replaced with other solvents instead of THF?
THF is generally the best choice due to its excellent stability and solubility. Diethyl ether can also be used as an alternative, but its stability is slightly lower. For industrial projects, THF is recommended as the primary solvent.
2. Is this reagent suitable for continuous flow reactions?
Some processes have successfully applied it to continuous flow systems, improving safety and reaction efficiency, but it is necessary to ensure that the equipment can meet anhydrous and oxygen-free conditions.
We are a professional Vinylmagnesium Chloride supplier. For more information or to purchase Vinylmagnesium Chloride(C2H3ClMg), please feel free to contact us via jomin@wolfabio.com.
