loading

Share to:
linkedin sharing button
facebook sharing button
whatsapp sharing button
line sharing button
kakao sharing button
wechat sharing button
sharethis sharing button

Vinylmagnesium Bromide Solution

Chemical Formula: C2H3BrMg
CAS: 1826-67-1

Vinylmagnesium Bromide Solution (C2H3BrMg) is a common Grignard reagent, usually existing in the form of diethyl ether or THF solution, and has a transparent light brown to brown appearance. Due to its high reactivity and good nucleophilic addition ability, Vinylmagnesium Bromide Solution is widely used in organic synthesis, pharmaceutical intermediate preparation, and polymerization-related research.
Availability:

Vinylmagnesium Bromide Solution Basic Properties

  • Molecular Formula: C2H3BrMg

  • Appearance: Transparent light brown to brown solution

  • Molecular Weight: 131.26

  • Density: 0.981 g/mL at 25 °C

  • Flash Point: 1 °F

  • Storage Conditions: Refrigerator

  • Solubility: Readily reacts with water, carbon dioxide, alcohols, aldehydes, ketones, esters, amines, and epoxides

  • Concentration: 1.0 M in THF

  • Package Information: 100g, 500g, 1kg or customized

Vinylmagnesium Bromide Solution Key Features

Highly reactive

Vinylmagnesium bromide solution exhibits outstanding nucleophilic addition properties, selectively adding to carbonyl compounds to generate allyl alcohols, making it an excellent reagent for constructing carbon-carbon bonds.

Excellent controllability

Compared to other vinyl metal reagents, it has a wider reaction temperature window, suitable for room temperature and low temperature conditions, which helps to avoid side reactions.

Wide range of applications

C2H3BrMg is a crucial vinyl source in organic synthesis, widely used in laboratory research and industrial production, including the synthesis of pharmaceutical active molecules, polymer monomers, and functional chemicals.

Excellent performance

Suitable for continuous reactions in scientific research, medicine, and industry, and performs well in scenarios with strict requirements for stability and metal impurities.

Vinylmagnesium Bromide Solution Main Applications

Pharmaceutical intermediates

C2H3BrMg can be used as a pharmaceutical intermediate to construct conjugated structures or addition skeletons, and is a common grammatical tool reagent in the drug raw material route.

Organic synthesis

It is mainly used as a strong nucleophile and vinylizing agent, and is widely used in the synthesis of pharmaceutical intermediates and fine chemicals.

Polymer materials

This compound can be used to synthesize specific monomers or polymer initiators/chain transfer agents to prepare polymer materials with specific structures and properties.

Research and development

Vinylmagnesium bromide solution is used as a model compound or starting material to synthesize other complex molecules and is widely applied in research fields such as catalysis chemistry and materials science.

Precautions

  1. Vinylmagnesium bromide solution reacts violently, even explosively, with water. All operations must be performed under strictly anhydrous conditions and protected with nitrogen or argon gas.

  2. All containers must be completely dry, otherwise the solution will decompose, affecting the reaction yield and reproducibility.

  3. If it gets on your skin, rinse immediately with plenty of water and remove any contaminated clothing. If it gets into your eyes, rinse continuously for at least 15 minutes and seek medical attention.

  4. C2H3BrMg reacts violently with oxidants, posing a risk of combustion or explosion, and should therefore be kept away from oxidizing substances.

  5. When adding it to a reaction vessel or flask, it should be added slowly dropwise to avoid local temperature rise that could lead to side reactions.

FAQ

1. What are the main uses of vinylmagnesium bromide solution?

It is primarily used as a Grignard reagent in organic synthesis as a vinylizing agent and nucleophile, and is widely used for carbon-carbon bond formation.


2. Can it be used directly for scale-up experiments?

Yes, but the feeding rate, temperature, and moisture content must be strictly controlled, and a small-scale test must be conducted beforehand to confirm the heat release of the reaction.


3. What is the difference between diethyl ether solution and THF solution?

Diethyl ether system is more volatile and suitable for low-boiling systems; THF has better stability and is suitable for a wider temperature range, and can be selected according to process requirements.


We are a professional Vinylmagnesium Bromide Solution supplier. For more information or to purchase Vinylmagnesium Bromide Solution(C2H3BrMg), please feel free to contact us via jomin@wolfabio.com.

Globally Recognized Provider of Integrated Solutions for High-end New Materials and Fine Chemicals

CONTACT US

 Phone:+86 18050950397
 Email:jomin@wolfabio.com
 WeChat:+86 18050950397
  WhatsApp:+86 18359103607
Address: 3901 Sansheng Tuscany, Nanyu Town, Minhou County, Fuzhou City, Fujian Province

QUICK LINKS

PRODUCTS CATEGORY

SIGN UP FOR OUR NEWSLETTER

Copyright © 2025 WOLFA All Rights Reserved
Leave a Message