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Molecular Formula: C₆H₅MgBr・(C₄H₈O)
Appearance: Light brown to dark brown solution
Molecular Weight: 181.31 g/mol
Solubility: Soluble in ether solvents such as THF and diethyl ether
Purity: 2N
Package Information: 100g, 500g, 1kg, or customized
Phenylmagnesium bromide tetrahydrofuran solution, as a typical Grignard reagent, can promote the nucleophilic addition of functional groups such as aldehydes, ketones, and esters with high reaction efficiency, making it one of the best choices for constructing aryl segments.
This compound exhibits high selectivity for many carbonyl compounds and performs exceptionally well in constructing aryl alcohols and aryl ketone derivatives, effectively improving the overall reaction yield.
THF provides a stable complexing environment, making the activity of Grignard reagents mild and controllable, and reducing the probability of inactivation or dangerous reactions due to exposure to air.
Used to construct important aryl fragments in drug structures, such as the synthesis of chiral alcohols, aryl heterocycles, and benzene ring substitution structures, it is a key step in many API synthetic routes.
It serves as an important nucleophilic addition reagent to enhance reaction efficiency in the directional construction of alcohols, esters, ketones, and various aromatic compounds.
It can be used to synthesize rigid aromatic skeletons such as terphenyl and tetraphenyl, or to prepare functional monomers containing phenyl side chains, and also participate in the Kumada coupling reaction.
Can react with heterocyclic carbonyl compounds to generate a range of functional materials and intermediates for use in new materials research or specialty chemical development.
Used to synthesize pesticide molecules with active functional groups, such as aryl alcohols, ketones, and directed substitution compounds, it is an important basic reagent in the agrochemical industry.
Phenylmagnesium bromide tetrahydrofuran solution decomposes violently upon contact with water, releasing flammable gases that may cause a fire. It should be handled in a strictly dry environment and kept away from water and humid air.
During operation, it should be kept strictly sealed. The container must be a waterproof and oxygen-proof chemical glass bottle or metal container. It is recommended to store it at low temperature in an inert atmosphere.
During operation, it should be kept strictly sealed. The container must be a waterproof and oxygen-proof chemical glass bottle or metal container. It is recommended to store it at low temperature in an inert atmosphere.
If it comes into contact with skin, rinse immediately with plenty of water and remove the contaminant. If it splashes into eyes, rinse thoroughly with water and seek medical attention immediately.
Grignard reagents, which contain strong reducing agents, can react violently and dangerously with oxidizing agents and must be stored separately.
The operation must be carried out in a fume hood to avoid inhaling THF vapors and any potentially escaping reactive gases.
1. What is Phenylmagnesium bromide tetrahydrofuran solution?
It is a reactive Grignard reagent stable in THF, used in nucleophilic addition reactions in organic synthesis, particularly for constructing aryl-carbon chain structures.
2. How to accurately titrate the true concentration of Phenylmagnesium Bromide Tetrahydrofuran Solution?
Under inert conditions, take a certain volume (V1) of the solution and add it to an excess of a standardized acid solution of known concentration (such as a THF solution of hydrochloric acid or benzoic acid). After the reaction is complete, back-titrate the remaining acid with a standard alkali solution (such as NaOH). Calculate the accurate concentration of the Grignard reagent based on the amount of acid consumed.
We are a professional Phenylmagnesium Bromide Tetrahydrofuran Solution supplier. For more information or to purchase Phenylmagnesium Bromide Tetrahydrofuran Solution, please feel free to contact us via jomin@wolfabio.com.
Molecular Formula: C₆H₅MgBr・(C₄H₈O)
Appearance: Light brown to dark brown solution
Molecular Weight: 181.31 g/mol
Solubility: Soluble in ether solvents such as THF and diethyl ether
Purity: 2N
Package Information: 100g, 500g, 1kg, or customized
Phenylmagnesium bromide tetrahydrofuran solution, as a typical Grignard reagent, can promote the nucleophilic addition of functional groups such as aldehydes, ketones, and esters with high reaction efficiency, making it one of the best choices for constructing aryl segments.
This compound exhibits high selectivity for many carbonyl compounds and performs exceptionally well in constructing aryl alcohols and aryl ketone derivatives, effectively improving the overall reaction yield.
THF provides a stable complexing environment, making the activity of Grignard reagents mild and controllable, and reducing the probability of inactivation or dangerous reactions due to exposure to air.
Used to construct important aryl fragments in drug structures, such as the synthesis of chiral alcohols, aryl heterocycles, and benzene ring substitution structures, it is a key step in many API synthetic routes.
It serves as an important nucleophilic addition reagent to enhance reaction efficiency in the directional construction of alcohols, esters, ketones, and various aromatic compounds.
It can be used to synthesize rigid aromatic skeletons such as terphenyl and tetraphenyl, or to prepare functional monomers containing phenyl side chains, and also participate in the Kumada coupling reaction.
Can react with heterocyclic carbonyl compounds to generate a range of functional materials and intermediates for use in new materials research or specialty chemical development.
Used to synthesize pesticide molecules with active functional groups, such as aryl alcohols, ketones, and directed substitution compounds, it is an important basic reagent in the agrochemical industry.
Phenylmagnesium bromide tetrahydrofuran solution decomposes violently upon contact with water, releasing flammable gases that may cause a fire. It should be handled in a strictly dry environment and kept away from water and humid air.
During operation, it should be kept strictly sealed. The container must be a waterproof and oxygen-proof chemical glass bottle or metal container. It is recommended to store it at low temperature in an inert atmosphere.
During operation, it should be kept strictly sealed. The container must be a waterproof and oxygen-proof chemical glass bottle or metal container. It is recommended to store it at low temperature in an inert atmosphere.
If it comes into contact with skin, rinse immediately with plenty of water and remove the contaminant. If it splashes into eyes, rinse thoroughly with water and seek medical attention immediately.
Grignard reagents, which contain strong reducing agents, can react violently and dangerously with oxidizing agents and must be stored separately.
The operation must be carried out in a fume hood to avoid inhaling THF vapors and any potentially escaping reactive gases.
1. What is Phenylmagnesium bromide tetrahydrofuran solution?
It is a reactive Grignard reagent stable in THF, used in nucleophilic addition reactions in organic synthesis, particularly for constructing aryl-carbon chain structures.
2. How to accurately titrate the true concentration of Phenylmagnesium Bromide Tetrahydrofuran Solution?
Under inert conditions, take a certain volume (V1) of the solution and add it to an excess of a standardized acid solution of known concentration (such as a THF solution of hydrochloric acid or benzoic acid). After the reaction is complete, back-titrate the remaining acid with a standard alkali solution (such as NaOH). Calculate the accurate concentration of the Grignard reagent based on the amount of acid consumed.
We are a professional Phenylmagnesium Bromide Tetrahydrofuran Solution supplier. For more information or to purchase Phenylmagnesium Bromide Tetrahydrofuran Solution, please feel free to contact us via jomin@wolfabio.com.
