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| Synonyms | PHENYLMAGNESIUM CHLORIDE;Phenylmagnesiumchloride,2-3MinTHF;chlorophenylmagnesium;Phenylchloromagnesium;Phenylmagnesium Chloride (27% in Tetrahydrofuran, ca. 2mol/L);Chlorphenylmagnesium; |
| Molecular Formula | C6H5ClMg |
| Appearance | Solution |
| Molecular Weight | 136.86 |
| Melting Point | 89-90℃ |
| Boiling Point | 230℃ (8 Torr) |
| Density | 0.98 g/mL at 20 °C |
| Flash Point | 1 °F |
| Storage Conditions | Water-free area |
| Purity | ≧ 98% |
| Package Information | 100g, 500g, 1kg, or customized |
Phenyl Magnesium Chloride, as a typical Grignard reagent, has extremely high nucleophilic addition ability to carbonyl compounds (such as aldehydes, ketones, esters, etc.), and is an important tool for constructing aromatic carbon skeletons.
Under strictly anhydrous and oxygen-free conditions, the reaction mechanism of this reagent is mature and highly predictable, facilitating scale-up experiments and the design of industrial-grade synthetic routes.
Phenyl Magnesium Chloride can serve as a universal aryl donor, widely participating in multi-step synthetic processes of drug molecules, functional materials, and fine chemicals.
The product has a mature manufacturing process and high batch stability, making it suitable for continuous use from R&D to pilot production and even commercial production.
Phenyl Magnesium Chloride is commonly used to synthesize pharmaceutical intermediates containing aryl groups. It reacts with aldehydes and ketones to generate the corresponding alcohol structures and is a key step in many API synthesis routes.
In the field of fine chemicals such as fragrances, functional molecules, and specialty additives, this compound is used to introduce phenyl structures to improve the stability or functionality of target molecules.
As a classic Grignard reagent, Phenyl Magnesium Chloride is widely used in organic synthesis research and teaching experiments in universities and research institutions to verify reaction mechanisms and synthetic strategies.
Phenyl Magnesium Chloride is extremely sensitive to moisture; it decomposes and becomes ineffective upon contact with water. Therefore, the storage and use environment must be kept absolutely dry.
It is recommended to store it in a sealed container in a cool, dry environment to avoid the risk of solvent evaporation or reaction caused by high temperatures.
Prolonged exposure to air may reduce the activity of the reagents; it is recommended to operate under the protection of an inert gas (such as nitrogen or argon).
This compound reacts rapidly with acids, alcohols, and amines, and should be stored in strict isolation.
Protective gloves and goggles must be worn during operation to avoid contact with the reagents on the skin and eyes.
If the substance accidentally comes into contact with skin or eyes, rinse immediately with plenty of water and seek medical attention as soon as possible.
1. What type of compound is Phenyl Magnesium Chloride?
It is a typical Grignard Reagent, belonging to the organomagnesium halide family. Its molecular weight is 136.86, its melting point is 89-90℃, and its boiling point is 230℃ (8 Torr). It is commonly used in nucleophilic addition reactions in organic synthesis.
2. In what form is Phenyl Magnesium Chloride typically supplied?
It is usually supplied as an ether or THF solution, rather than a pure solid.
3. What are the advantages of Phenyl Magnesium Chloride compared to other aryl Grignard reagents?
Its reaction mechanism is more mature, its source is stable, and its application range is wide, making it one of the most basic and commonly used aryl Grignard reagents.
4. Can this compound be used for industrial scale-up?
Under mature anhydrous operating systems and safe control conditions, it can be used for pilot-scale and industrial-scale synthesis.
5. What are its storage requirements?
This compound must be stored in a sealed container under anhydrous and oxygen-free conditions, avoiding high temperatures, humidity, and contact with air.
Wolfa professionally supplies Phenyl Magnesium Chloride, supporting small-batch sampling and large-volume procurement needs. Packaging options include ordinary glass bottles, glass ampoules, metal ampoules, etc.
For product analysis reports (such as COA) or procurement consulting, please feel free to contact us at jomin@wolfabio.com at any time.
| Synonyms | PHENYLMAGNESIUM CHLORIDE;Phenylmagnesiumchloride,2-3MinTHF;chlorophenylmagnesium;Phenylchloromagnesium;Phenylmagnesium Chloride (27% in Tetrahydrofuran, ca. 2mol/L);Chlorphenylmagnesium; |
| Molecular Formula | C6H5ClMg |
| Appearance | Solution |
| Molecular Weight | 136.86 |
| Melting Point | 89-90℃ |
| Boiling Point | 230℃ (8 Torr) |
| Density | 0.98 g/mL at 20 °C |
| Flash Point | 1 °F |
| Storage Conditions | Water-free area |
| Purity | ≧ 98% |
| Package Information | 100g, 500g, 1kg, or customized |
Phenyl Magnesium Chloride, as a typical Grignard reagent, has extremely high nucleophilic addition ability to carbonyl compounds (such as aldehydes, ketones, esters, etc.), and is an important tool for constructing aromatic carbon skeletons.
Under strictly anhydrous and oxygen-free conditions, the reaction mechanism of this reagent is mature and highly predictable, facilitating scale-up experiments and the design of industrial-grade synthetic routes.
Phenyl Magnesium Chloride can serve as a universal aryl donor, widely participating in multi-step synthetic processes of drug molecules, functional materials, and fine chemicals.
The product has a mature manufacturing process and high batch stability, making it suitable for continuous use from R&D to pilot production and even commercial production.
Phenyl Magnesium Chloride is commonly used to synthesize pharmaceutical intermediates containing aryl groups. It reacts with aldehydes and ketones to generate the corresponding alcohol structures and is a key step in many API synthesis routes.
In the field of fine chemicals such as fragrances, functional molecules, and specialty additives, this compound is used to introduce phenyl structures to improve the stability or functionality of target molecules.
As a classic Grignard reagent, Phenyl Magnesium Chloride is widely used in organic synthesis research and teaching experiments in universities and research institutions to verify reaction mechanisms and synthetic strategies.
Phenyl Magnesium Chloride is extremely sensitive to moisture; it decomposes and becomes ineffective upon contact with water. Therefore, the storage and use environment must be kept absolutely dry.
It is recommended to store it in a sealed container in a cool, dry environment to avoid the risk of solvent evaporation or reaction caused by high temperatures.
Prolonged exposure to air may reduce the activity of the reagents; it is recommended to operate under the protection of an inert gas (such as nitrogen or argon).
This compound reacts rapidly with acids, alcohols, and amines, and should be stored in strict isolation.
Protective gloves and goggles must be worn during operation to avoid contact with the reagents on the skin and eyes.
If the substance accidentally comes into contact with skin or eyes, rinse immediately with plenty of water and seek medical attention as soon as possible.
1. What type of compound is Phenyl Magnesium Chloride?
It is a typical Grignard Reagent, belonging to the organomagnesium halide family. Its molecular weight is 136.86, its melting point is 89-90℃, and its boiling point is 230℃ (8 Torr). It is commonly used in nucleophilic addition reactions in organic synthesis.
2. In what form is Phenyl Magnesium Chloride typically supplied?
It is usually supplied as an ether or THF solution, rather than a pure solid.
3. What are the advantages of Phenyl Magnesium Chloride compared to other aryl Grignard reagents?
Its reaction mechanism is more mature, its source is stable, and its application range is wide, making it one of the most basic and commonly used aryl Grignard reagents.
4. Can this compound be used for industrial scale-up?
Under mature anhydrous operating systems and safe control conditions, it can be used for pilot-scale and industrial-scale synthesis.
5. What are its storage requirements?
This compound must be stored in a sealed container under anhydrous and oxygen-free conditions, avoiding high temperatures, humidity, and contact with air.
Wolfa professionally supplies Phenyl Magnesium Chloride, supporting small-batch sampling and large-volume procurement needs. Packaging options include ordinary glass bottles, glass ampoules, metal ampoules, etc.
For product analysis reports (such as COA) or procurement consulting, please feel free to contact us at jomin@wolfabio.com at any time.
