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| Synonyms | tert-butylmagnesium chloride solution;TERT-BUTYLMAGNESIUM CHLORIDE: (26% IN ETHYL ETHER, CA. 2MOL/L);solution~1MinTHF;t-Butylmagnesium Chloride 1.0 M In Butyl Diglyme;TERT-BUTYLMAGNESIUM CHLORIDE;T-BUTYLMAGNESIUM CHLORIDE |
| Molecular Formula | C4H9ClMg |
| Appearance | Transparent brown to dark brown liquid |
| Molecular Weight | 116.87 |
| Melting Point | -108℃ (Tetrahydrofuran) |
| Density | 0.931 g/mL at 25 °C |
| Flash Point | 34 °F |
| Storage Conditions | 2-8°C, nitrogen protection |
| Purity | ≧ 98% |
| Package Information | 100g, 500g, 1kg, or customized |
This reagent can efficiently introduce the tert-butyl group into target molecules and has unique advantages in regulating steric hindrance, molecular stability, and physicochemical properties.
Tert-Butylmagnesium Chloride combines significant nucleophilicity with strong basicity, making it suitable for organic transformation systems requiring high reactivity.
It can undergo addition reactions with a variety of carbonyl compounds such as aldehydes, ketones, and esters, offering high application flexibility.
As a commonly used alkyl Grignard reagent, its reaction mechanism is well-defined, with abundant literature and process experience, facilitating the transition from the laboratory to the pilot-scale stage.
Tert-Butylmagnesium Chloride is commonly used in the synthesis of pharmaceutical molecules to improve the stability, metabolic properties, or spatial configuration of drug molecules by introducing a tert-butyl group.
In the research and development of specialty chemicals and functional materials, this compound is used to construct high-carbon-barrier frameworks or as a key reaction intermediate.
In the scientific research field, Tert-Butylmagnesium Chloride is widely used to study Grignard reaction mechanisms, reaction selectivity, and the exploration of novel organic synthesis pathways.
This reagent is extremely sensitive to moisture, which can easily lead to its decomposition and inactivation. Therefore, the operating environment must be kept completely dry.
Prolonged exposure to air may cause a decrease in the reactivity of the reagent; it is recommended to transfer and use it under the protection of an inert gas.
It should be sealed and stored in a cool, dry environment to avoid high temperatures that could cause solvent evaporation or increase the risk of reaction.
Because it readily reacts violently with acids and substances containing active hydrogen, it must be stored in strictly separate areas.
Protective gloves, safety glasses, and lab coats must be worn during operation to prevent reagents from coming into contact with the skin and eyes.
If accidentally contacted, rinse immediately with plenty of water and seek medical attention promptly.
1. What is Tert-Butylmagnesium Chloride?
It is a typical alkyl Grignard Reagent, belonging to the organomagnesium halide family. Its molecular weight is 116.87, and its melting point is -108°C (Tetrahydrofuran).
2. What are the characteristics of this reagent compared to aryl Grignard reagents?
It is more basic and has greater steric hindrance, making it suitable for specific structure construction and highly reactive systems.
3. What are the most significant risks to be aware of during storage?
Moisture, air, and high temperature are the primary risk factors; therefore, strict control of the storage and usage environment is essential.
Wolfa professionally supplies Tert-Butylmagnesium Chloride, supporting small-batch sampling and large-volume procurement needs. Packaging options include ordinary glass bottles, glass ampoules, metal ampoules, etc.
For product analysis reports (such as COA) or procurement consulting, please feel free to contact us at jomin@wolfabio.com at any time.
| Synonyms | tert-butylmagnesium chloride solution;TERT-BUTYLMAGNESIUM CHLORIDE: (26% IN ETHYL ETHER, CA. 2MOL/L);solution~1MinTHF;t-Butylmagnesium Chloride 1.0 M In Butyl Diglyme;TERT-BUTYLMAGNESIUM CHLORIDE;T-BUTYLMAGNESIUM CHLORIDE |
| Molecular Formula | C4H9ClMg |
| Appearance | Transparent brown to dark brown liquid |
| Molecular Weight | 116.87 |
| Melting Point | -108℃ (Tetrahydrofuran) |
| Density | 0.931 g/mL at 25 °C |
| Flash Point | 34 °F |
| Storage Conditions | 2-8°C, nitrogen protection |
| Purity | ≧ 98% |
| Package Information | 100g, 500g, 1kg, or customized |
This reagent can efficiently introduce the tert-butyl group into target molecules and has unique advantages in regulating steric hindrance, molecular stability, and physicochemical properties.
Tert-Butylmagnesium Chloride combines significant nucleophilicity with strong basicity, making it suitable for organic transformation systems requiring high reactivity.
It can undergo addition reactions with a variety of carbonyl compounds such as aldehydes, ketones, and esters, offering high application flexibility.
As a commonly used alkyl Grignard reagent, its reaction mechanism is well-defined, with abundant literature and process experience, facilitating the transition from the laboratory to the pilot-scale stage.
Tert-Butylmagnesium Chloride is commonly used in the synthesis of pharmaceutical molecules to improve the stability, metabolic properties, or spatial configuration of drug molecules by introducing a tert-butyl group.
In the research and development of specialty chemicals and functional materials, this compound is used to construct high-carbon-barrier frameworks or as a key reaction intermediate.
In the scientific research field, Tert-Butylmagnesium Chloride is widely used to study Grignard reaction mechanisms, reaction selectivity, and the exploration of novel organic synthesis pathways.
This reagent is extremely sensitive to moisture, which can easily lead to its decomposition and inactivation. Therefore, the operating environment must be kept completely dry.
Prolonged exposure to air may cause a decrease in the reactivity of the reagent; it is recommended to transfer and use it under the protection of an inert gas.
It should be sealed and stored in a cool, dry environment to avoid high temperatures that could cause solvent evaporation or increase the risk of reaction.
Because it readily reacts violently with acids and substances containing active hydrogen, it must be stored in strictly separate areas.
Protective gloves, safety glasses, and lab coats must be worn during operation to prevent reagents from coming into contact with the skin and eyes.
If accidentally contacted, rinse immediately with plenty of water and seek medical attention promptly.
1. What is Tert-Butylmagnesium Chloride?
It is a typical alkyl Grignard Reagent, belonging to the organomagnesium halide family. Its molecular weight is 116.87, and its melting point is -108°C (Tetrahydrofuran).
2. What are the characteristics of this reagent compared to aryl Grignard reagents?
It is more basic and has greater steric hindrance, making it suitable for specific structure construction and highly reactive systems.
3. What are the most significant risks to be aware of during storage?
Moisture, air, and high temperature are the primary risk factors; therefore, strict control of the storage and usage environment is essential.
Wolfa professionally supplies Tert-Butylmagnesium Chloride, supporting small-batch sampling and large-volume procurement needs. Packaging options include ordinary glass bottles, glass ampoules, metal ampoules, etc.
For product analysis reports (such as COA) or procurement consulting, please feel free to contact us at jomin@wolfabio.com at any time.
