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Molecular Formula: C3H7BrMg
Appearance: Clear dark brown or dark gray solution
Molecular Weight: 147.3
Melting Point: 114-116℃
Boiling Point: 148-154℃
Density: 0.982 g/mL at 25 °C
Flash Point: -17°C
Storage Conditions: 2-8°C
Solubility: Miscible with tetrahydrofuran and diethyl ether, immiscible with hydrocarbons
Package Information: 100g, 500g, 1kg, or customized
As a strong nucleophile, C3H7BrMg can react efficiently with various functional groups such as aldehydes, ketones, and esters, specifically introducing isopropyl groups, effectively reducing side reactions, and improving the purity and yield of the target product.
Isopropylmagnesium Bromide is commonly supplied in THF and diethyl ether solutions, making it compatible with a variety of industrial reaction systems and reducing process adjustment costs.
As a mature Grignard reagent, it can be smoothly scaled up from laboratory scale to ton-scale production, suitable for large-scale synthesis needs in the pharmaceutical, agrochemical, and materials fields.
Isopropylmagnesium Bromide is widely used in the preparation of pharmaceutical intermediates with chiral centers or special configurations, such as the construction of alcohols, tertiary alcohols, and alkylated structural units. It is an indispensable tool reagent in many API routes.
It can be used in various alkylation, addition, and coupling reactions, and is especially suitable for the selective addition of carbonyl compounds, helping to construct complex molecular skeletons.
Used in the synthesis of certain functional polymers, specialty monomers, or material additives, C3H7BrMg can participate in initiation or construction of key chain segments.
It can be used as a standard Grignard reagent to verify the C–C bond formation mechanism and the performance of novel catalytic systems.
Isopropylmagnesium Bromide decomposes rapidly upon contact with water, generating heat and flammable gases. Therefore, it must be stored in an inert atmosphere (nitrogen or argon), and the system must be thoroughly dried.
It is recommended to store in a cool, dry environment (generally 2-8℃) and keep the container sealed to avoid decomposition caused by light and temperature fluctuations.
It is strictly forbidden to mix it directly with water, alcohol, acid, compounds containing active hydrogen (such as alkynes), or halogenated hydrocarbons (unless a specific reaction occurs), otherwise it may cause a violent or even explosive reaction.
High temperatures can trigger decomposition reactions, leading to potential safety risks; therefore, handle with care during transportation and transfer.
It is highly reactive and may release flammable vapors; it must be operated in a chemical fume hood or inert gas protection system.
1. What is Isopropylmagnesium Bromide?
Isopropylmagnesium Bromide is a Grignard reagent (organomagnesium reagent) commonly used in the construction of C–C bonds and is an important reaction tool in organic synthesis.
2. Why is Isopropylmagnesium Bromide usually supplied as a solution?
Because its solid form is extremely unstable and easily affected by air and moisture, it is typically supplied industrially as a solution prepared with THF or ether solvents.
3. What are the typical applications of Isopropylmagnesium Bromide?
It is mainly used in the synthesis of pharmaceutical intermediates, fine chemicals, and monomers for specialty materials. It is also widely used in carbonyl addition, alkylation, and coupling reactions.
We are a professional Isopropylmagnesium Bromide supplier. For more information or to purchase Isopropylmagnesium Bromide(C3H7BrMg), please feel free to contact us via jomin@wolfabio.com.
Molecular Formula: C3H7BrMg
Appearance: Clear dark brown or dark gray solution
Molecular Weight: 147.3
Melting Point: 114-116℃
Boiling Point: 148-154℃
Density: 0.982 g/mL at 25 °C
Flash Point: -17°C
Storage Conditions: 2-8°C
Solubility: Miscible with tetrahydrofuran and diethyl ether, immiscible with hydrocarbons
Package Information: 100g, 500g, 1kg, or customized
As a strong nucleophile, C3H7BrMg can react efficiently with various functional groups such as aldehydes, ketones, and esters, specifically introducing isopropyl groups, effectively reducing side reactions, and improving the purity and yield of the target product.
Isopropylmagnesium Bromide is commonly supplied in THF and diethyl ether solutions, making it compatible with a variety of industrial reaction systems and reducing process adjustment costs.
As a mature Grignard reagent, it can be smoothly scaled up from laboratory scale to ton-scale production, suitable for large-scale synthesis needs in the pharmaceutical, agrochemical, and materials fields.
Isopropylmagnesium Bromide is widely used in the preparation of pharmaceutical intermediates with chiral centers or special configurations, such as the construction of alcohols, tertiary alcohols, and alkylated structural units. It is an indispensable tool reagent in many API routes.
It can be used in various alkylation, addition, and coupling reactions, and is especially suitable for the selective addition of carbonyl compounds, helping to construct complex molecular skeletons.
Used in the synthesis of certain functional polymers, specialty monomers, or material additives, C3H7BrMg can participate in initiation or construction of key chain segments.
It can be used as a standard Grignard reagent to verify the C–C bond formation mechanism and the performance of novel catalytic systems.
Isopropylmagnesium Bromide decomposes rapidly upon contact with water, generating heat and flammable gases. Therefore, it must be stored in an inert atmosphere (nitrogen or argon), and the system must be thoroughly dried.
It is recommended to store in a cool, dry environment (generally 2-8℃) and keep the container sealed to avoid decomposition caused by light and temperature fluctuations.
It is strictly forbidden to mix it directly with water, alcohol, acid, compounds containing active hydrogen (such as alkynes), or halogenated hydrocarbons (unless a specific reaction occurs), otherwise it may cause a violent or even explosive reaction.
High temperatures can trigger decomposition reactions, leading to potential safety risks; therefore, handle with care during transportation and transfer.
It is highly reactive and may release flammable vapors; it must be operated in a chemical fume hood or inert gas protection system.
1. What is Isopropylmagnesium Bromide?
Isopropylmagnesium Bromide is a Grignard reagent (organomagnesium reagent) commonly used in the construction of C–C bonds and is an important reaction tool in organic synthesis.
2. Why is Isopropylmagnesium Bromide usually supplied as a solution?
Because its solid form is extremely unstable and easily affected by air and moisture, it is typically supplied industrially as a solution prepared with THF or ether solvents.
3. What are the typical applications of Isopropylmagnesium Bromide?
It is mainly used in the synthesis of pharmaceutical intermediates, fine chemicals, and monomers for specialty materials. It is also widely used in carbonyl addition, alkylation, and coupling reactions.
We are a professional Isopropylmagnesium Bromide supplier. For more information or to purchase Isopropylmagnesium Bromide(C3H7BrMg), please feel free to contact us via jomin@wolfabio.com.
