Tetrakis (Triphenylphosphine) Nickel

Tetrakis (Triphenylphosphine) Nickel Basic Properties

• Molecular Formula: C72H60NiP4

• Appearance: Rust-brown to brown fine powder

• Molecular Weight: 1107.84

• Melting Point: 123-128°C

• Solubility: Insoluble in water

• Storage Conditions: Inert atmosphere, room Temperature

• Package Information: 100g, 500g, 1kg or customized

Tetrakis (Triphenylphosphine) Nickel Key Features

Solid nickel source

Ni(PPh3)4 is a solid nickel source, which is more convenient to weigh and handle than liquid nickel, providing convenience for laboratory research and industrial production.

High activity

Tetrakis (triphenylphosphine) nickel serves as the active center in homogeneous catalytic systems, providing excellent reactivity and making it suitable for various nickel-catalyzed catalytic systems.

High reaction selectivity

In specific reactions, such as catalyzing the dimerization of 1,2-allenes or the trimerization of enynes, Ni(PPh3)4 exhibits extremely high chemoselectivity, preferentially generating specific cyclic or aromatic products and avoiding the formation of complex byproducts.

Adaptability to multiple reaction systems

This compound is suitable for systems involving haloalkanes, aryl halides, and carbon-carbon bond construction reactions, and is compatible with a variety of functional groups.

Tetrakis (Triphenylphosphine) Nickel Main Applications

Organic synthesis

Ni(PPh3)4 serves as a core catalyst in organic synthesis, widely used in C-C bond coupling reactions such as the Friedel-Crafts reaction and the Suzuki coupling reaction.

Synthesis of pharmaceutical intermediates

This compound is used in medicinal chemistry research to construct complex aromatic and heterocyclic frameworks, thereby improving synthetic efficiency.

Polymer and materials chemistry

Used for polymerization reactions, electronic material precursor development, and particularly suitable for functional polymer chain design.

Precautions

1. Tetrakis (triphenylphosphine) nickel is sensitive to air and moisture. Prolonged exposure to air will cause it to deactivate or even decompose rapidly. All operations must be carried out in a glove box or vacuum line under inert gas protection (such as nitrogen or argon).

2. It should be stored at room temperature in an inert atmosphere, and the container should be tightly sealed to avoid humid environments, heat sources and open flames.

3. Always wear appropriate personal protective equipment when handling this product to avoid injury.

4. If the product comes into contact with skin or eyes, immediately rinse with plenty of water for at least 15 minutes and seek medical attention promptly.

5. Nickel-containing waste liquid and reaction residues must be treated as heavy metal organic reagents and direct discharge is prohibited.

FAQ

1. Can Ni(PPh3)4 be used directly in the Suzuki reaction?

Yes, it can be used directly as a zero-valent nickel catalyst, but in some systems, additional ligands and bases are required for adjustment.

2. Can this product replace Pd catalysts?

It can replace them in some coupling systems at a lower cost, but the system optimization conditions need to be more controlled, especially sensitive to substrate structure and ligand ratio.

For more information or to purchase Tetrakis (Triphenylphosphine) Nickel(Ni(PPh3)4), please feel free to contact us via jomin@wolfabio.com or WhatsApp(+86 18359103607).