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| Synonyms | CS-2285;N-[(1S,2R)-2-Hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[[4-(4-morpholinylmethyl)phenyl]ethynyl]benzamide;Benzamide, N-[(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]- |
| Molecular Formula | C24H27N3O5 |
| Appearance | White to off-white solid |
| Molecular Weight | 437.488 |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Acidity Coefficient (pKa) | 9.11±0.40(Predicted) |
| Storage Conditions | -20°C |
| Solubility | ≥21.85 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
| Purity | ≧ 98% |
| Package Information | 100g, 500g, 1kg, or customized |
Chir-090 specifically inhibits LpxC, a key rate-limiting enzyme in the lipopolysaccharide (LPS) biosynthesis pathway of Gram-negative bacteria, making it an important molecular tool for studying LPS biosynthesis.
Its chemical structure is well-defined, and its molecular weight is moderate, facilitating structure-activity relationship (SAR) studies and the design of related derivatives.
Because LpxC is highly conserved in various Gram-negative bacteria, Chir-090 is widely used in antibacterial target validation and studies on the mechanism of action.
Chir-090 has been reported in numerous academic publications and possesses excellent research traceability, making it suitable for long-term use by universities and research institutions.
Chir-090 is commonly used to study the LPS biosynthesis pathway and helps to elucidate the function of LpxC in bacterial cell wall construction.
In microbiology, pharmacology, and chemical biology research, Chir-090 is used to explore the interactions between small-molecule inhibitors and enzyme targets.
In the development of new antimicrobial drugs, Chir-090 can be used as a positive control compound to validate the feasibility of LpxC as an antimicrobial target.
By inhibiting LPS synthesis, this compound can be used to study bacterial growth inhibition and related resistance mechanisms.
Chir-090 is for research and in vitro experiments only and should not be used for clinical or human-related applications.
It is recommended to store the product in a sealed container in a cool, dry, and dark environment. For long-term storage, it can be kept at -20 °C to ensure stability.
Because it is sensitive to light and moisture, it should be protected from prolonged exposure to air.
Protective gloves and safety glasses must be worn during operation to prevent inhalation of the powder or direct contact with the skin and eyes.
If accidental contact occurs, immediately rinse with plenty of water and seek medical attention if necessary.
Experimental waste should be disposed of in accordance with local regulations regarding research chemicals or organic small molecule waste, and must not be disposed of indiscriminately.
1. What is Chir-090?
Chir-090 is a small molecule LpxC inhibitor with a molecular weight of 437.488 and a predicted density of 1.33 ± 0.1 g/cm³. It is primarily used in research related to lipopolysaccharide biosynthesis and antibacterial mechanisms in Gram-negative bacteria.
2. Is Chir-090 an antibiotic?
It is not a clinical antibiotic itself, but rather a research tool compound used in the development and mechanistic studies of antibacterial drugs.
3. Is Chir-090 suitable for long-term storage?
When stored under sealed, light-protected, and low-temperature conditions, it maintains good chemical stability and is suitable for long-term use in research.
4. What are the main research uses of Chir-090?
It is primarily used in LpxC target research, antibacterial drug screening, and basic research on bacterial lipopolysaccharide synthesis pathways.
Wolfa professionally supplies Chir-090, supporting small-batch sampling and large-volume procurement needs. Packaging options include ordinary glass bottles, glass ampoules, metal ampoules, etc.
For product analysis reports (such as COA) or procurement consulting, please feel free to contact us at jomin@wolfabio.com at any time.
| Synonyms | CS-2285;N-[(1S,2R)-2-Hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[[4-(4-morpholinylmethyl)phenyl]ethynyl]benzamide;Benzamide, N-[(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]- |
| Molecular Formula | C24H27N3O5 |
| Appearance | White to off-white solid |
| Molecular Weight | 437.488 |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Acidity Coefficient (pKa) | 9.11±0.40(Predicted) |
| Storage Conditions | -20°C |
| Solubility | ≥21.85 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
| Purity | ≧ 98% |
| Package Information | 100g, 500g, 1kg, or customized |
Chir-090 specifically inhibits LpxC, a key rate-limiting enzyme in the lipopolysaccharide (LPS) biosynthesis pathway of Gram-negative bacteria, making it an important molecular tool for studying LPS biosynthesis.
Its chemical structure is well-defined, and its molecular weight is moderate, facilitating structure-activity relationship (SAR) studies and the design of related derivatives.
Because LpxC is highly conserved in various Gram-negative bacteria, Chir-090 is widely used in antibacterial target validation and studies on the mechanism of action.
Chir-090 has been reported in numerous academic publications and possesses excellent research traceability, making it suitable for long-term use by universities and research institutions.
Chir-090 is commonly used to study the LPS biosynthesis pathway and helps to elucidate the function of LpxC in bacterial cell wall construction.
In microbiology, pharmacology, and chemical biology research, Chir-090 is used to explore the interactions between small-molecule inhibitors and enzyme targets.
In the development of new antimicrobial drugs, Chir-090 can be used as a positive control compound to validate the feasibility of LpxC as an antimicrobial target.
By inhibiting LPS synthesis, this compound can be used to study bacterial growth inhibition and related resistance mechanisms.
Chir-090 is for research and in vitro experiments only and should not be used for clinical or human-related applications.
It is recommended to store the product in a sealed container in a cool, dry, and dark environment. For long-term storage, it can be kept at -20 °C to ensure stability.
Because it is sensitive to light and moisture, it should be protected from prolonged exposure to air.
Protective gloves and safety glasses must be worn during operation to prevent inhalation of the powder or direct contact with the skin and eyes.
If accidental contact occurs, immediately rinse with plenty of water and seek medical attention if necessary.
Experimental waste should be disposed of in accordance with local regulations regarding research chemicals or organic small molecule waste, and must not be disposed of indiscriminately.
1. What is Chir-090?
Chir-090 is a small molecule LpxC inhibitor with a molecular weight of 437.488 and a predicted density of 1.33 ± 0.1 g/cm³. It is primarily used in research related to lipopolysaccharide biosynthesis and antibacterial mechanisms in Gram-negative bacteria.
2. Is Chir-090 an antibiotic?
It is not a clinical antibiotic itself, but rather a research tool compound used in the development and mechanistic studies of antibacterial drugs.
3. Is Chir-090 suitable for long-term storage?
When stored under sealed, light-protected, and low-temperature conditions, it maintains good chemical stability and is suitable for long-term use in research.
4. What are the main research uses of Chir-090?
It is primarily used in LpxC target research, antibacterial drug screening, and basic research on bacterial lipopolysaccharide synthesis pathways.
Wolfa professionally supplies Chir-090, supporting small-batch sampling and large-volume procurement needs. Packaging options include ordinary glass bottles, glass ampoules, metal ampoules, etc.
For product analysis reports (such as COA) or procurement consulting, please feel free to contact us at jomin@wolfabio.com at any time.
