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Magnesium Bromide丨CAS 7789-48-2

CAS: 7789-48-2
Chemical Formula: MgBr2

Magnesium Bromide (MgBr2) is a white, hygroscopic, anhydrous powder renowned for its excellent solubility and reactivity. It is widely used in organic synthesis, reagent preparation, catalysis, and high-end materials processing. Due to its high purity and controllability, Magnesium Bromide has become an important basic raw material for the fine chemical and pharmaceutical industries.
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Magnesium Bromide Basic Properties

SynonymsMAGNESIUM BROMIDE;Hydrobromic acid magnesium salt;Magnesium bromide (MgBr2);MgBr2;Magnesiumbromide,anhydrous,98%
Molecular FormulaMgBr2
AppearanceOff-white powder
Molecular Weight184.11
Melting Point711 °C(lit.)
Boiling Point1248.47°C (estimate)
Density3.72 g/mL at 25 °C(lit.)
SolubilityDMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
Purity≧ 98%
Package Information100g, 500g, 1kg, or customized

Magnesium Bromide Key Features

High reactivity

Due to the excellent dissociation properties of MgBr2, it can rapidly participate in nucleophilic, electrophilic, or coordination processes in organic reactions, thereby improving reaction efficiency and yield.

High solubility

Magnesium Bromide exhibits excellent solubility in polar solvents, making it readily applicable to solution reaction systems. This reduces the risk of side reactions caused by solid impurities and facilitates more precise control of reaction conditions.

Controllable purity

High-purity MgBr2 meets the extremely high requirements for impurity content in industries such as pharmaceuticals, electronic chemicals, and OLED intermediates, ensuring the stability, safety, and consistency of the final product.

Excellent coordination ability

This compound can act as a mild Lewis acid in many types of reactions, which helps to improve reaction selectivity and catalytic efficiency, and reduce over-reaction or by-product formation.

Magnesium Bromide Main Applications

Organic synthesis reactions

MgBr2 is used as an electrophile, catalyst, or Lewis acid in esterification, hydroxyl protection, alkylation, amination, and various rearrangement reactions. It is a commonly used metal halide in laboratory and industrial synthesis.

Pharmaceutical intermediates

Due to their mild reaction and high controllability, Magnesium Bromide is often used to synthesize complex molecular structures, such as heterocyclic compounds and aromatic substitutes, and is an important step in many API (Active Pharmaceutical Ingredients) routes.

Materials chemistry

It is used for Brønsted acid regulation in polymer modification, surface treatment, and electrochemical materials, and is also applied in the research of novel passivating agents and flame retardant formulations.

Analytical chemistry and reagents

MgBr2 can be used to prepare special coordination reagents, titration reagents, or as a solvent treatment agent under anhydrous conditions, and is particularly suitable for water-sensitive reaction systems.

Precautions

  1. Magnesium Bromide is highly hygroscopic and deliquescent, which can lead to a decrease in purity. Therefore, it must be stored in a sealed, moisture-proof, and dry environment, avoiding exposure to air.

  2. Contact with strong oxidants may cause dangerous reactions; strong bases may damage its structure or reduce its reactivity.

  3. MgBr2 solution is irritating to the skin and eyes. If contact occurs, rinse immediately with plenty of water and seek medical attention if necessary.

  4. Inhaling dust may cause respiratory irritation. It is recommended to use a local exhaust ventilation system and wear a dust mask during operation.

  5. When used in anhydrous reaction systems, it must be used under argon or nitrogen protection to avoid moisture affecting the critical reaction results.

FAQ

1. What is Magnesium Bromide?

Magnesium bromide is an inorganic magnesium salt, usually a white, hygroscopic solid, commonly used in organic synthesis and reagent preparation. Its chemical formula is MgBr2, CAS number is 7789-48-2, molecular weight is 184.11, melting point is 184.11, and density is 3.72 g/mL at 25 °C (lit.).


2. What is the difference between MgBr2 and MgBr2·6H2O?

Anhydrous MgBr2 is suitable for water-sensitive reactions; hydrated MgBr2·6H2O is suitable for ordinary solution systems. Their purity and applications differ, and the choice should be based on process requirements.


3. What reactions can Magnesium Bromide be used for?

It is suitable for a variety of reactions, including esterification, alkylation, amination, rearrangement, hydroxyl protection, and Lewis acid catalysis.


4. How to safely and effectively open and use a bottle of Magnesium Bromide?

The best practice is to operate in a glove box (water and oxygen content <1 ppm). In a standard laboratory setting, a rapid procedure is required: quickly transfer the original bottle to a large plastic bag or operating box filled with a dry, inert gas (such as argon), open it from the inside, remove the required amount, and immediately reseal the inner and outer packaging. The removed sample should also be immediately placed in a sealed container.


Wolfa professionally supplies Magnesium Bromide, supporting small-batch sampling and large-volume procurement needs. Packaging options include ordinary glass bottles, glass ampoules, metal ampoules, etc.


For product analysis reports (such as COA) or procurement consulting, please feel free to contact us at jomin@wolfabio.com at any time.

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